The Science Advancing Specimen Integrity Testing
VDx helps laboratories and testing programs identify synthetic urine, detox‑product adulteration, advanced oxidants, and other forms of drug‑test subversion that standard validity testing may not reveal.
Explore the ScienceWe Detect the Subversion That Is Outsmarting Drug Testing
Specimen Validity Testing (SVT) determines whether a urine drug specimen has been adulterated, diluted, or substituted. Standard specimen validity testing was designed decades ago — and the people trying to beat drug tests have long since outsmarted it.
The VDx Essentials Panel catches the subversion that standard testing misses — including synthetic urine — in your own laboratory.
Our SolutionStandard Specimen Validity Testing
Checks pH, creatinine and specific gravity. It catches dilution — but synthetic urine passes straight through.
The VDx Essentials Panel
Adds adulterant and synthetic‑urine detection to the standard checks, so a subverted specimen is flagged instead of reported as clean.
Detect Synthetic Urine
Quickly and accurately identify counterfeit urine that standard pH, creatinine and specific gravity checks cannot see — before it corrupts your results.
Reduce False Negatives
A subverted specimen turns a positive drug screen into a false negative. Catch the subversion, and the result your lab reports reflects the patient.
Increase Compliance
Accurate validity results support prescribing decisions, honest treatment conversations, and medication limitations.
Why Accurate Detection Matters
The Essentials Panel
Six tests that together show whether a specimen is real. VDx reagents are currently implemented on Beckman Coulter, Olympus AU, Thermo Fisher Indiko Plus, Carolina Liquid Chemistries CLC1600, and Siemens Atellica analyzers.

Creatinine, pH & Specific Gravity Index
The standard checks for dilution and gross adulteration — the baseline every specimen should pass.

Oxidants Can Disappear in Hours. VDx Looks Back Up to 30 Days.
Traditional oxidant tests detect the oxidant only while it remains in the specimen, often a matter of hours. VDx Oxidant History expands that detection window up to 30 days, helping laboratories identify prior oxidant use after the original oxidant is no longer present.

True Urine™ Synthetic Detection
Patented Short and Long Duration assays that catch counterfeit urine — which standard pH, creatinine and specific gravity checks cannot.
Subversion Is Beating Your Lab
Providing accurate data is the most important thing a lab does. If your lab reports bad data, the outcomes downstream are bad too — drug courts, rehabilitation programs and clinics all rely on laboratory results to decide a patient’s next step.
Better detection means better outcomes. We help your lab expose:
- Patients and donors attempting to subvert drug-testing results
- Synthetic urine submitted in place of a real specimen
- Patients showing positive for one drug while taking another
- Pills getting into the wrong hands
What Laboratories Are Finding
“Using the classic trio of creatinine, pH, and specific gravity, only about 5% of the samples would have failed the panel. Using your SVT Panel, a whopping 16% failed the panel.”R.BCertified Toxicologist
“Now that we are utilizing cutting edge science, our laboratory now has a serious advantage versus the competition…”E.D.Reference Laboratory
“Before I was getting false laboratory intelligence and potentially prescribing to [patients subverting their tests]. Now that I am detecting [subversion], I am finally having the needed patient conversations, ‘Let’s talk about Treatment’.”A.A.Physician
Current Analyzer Implementations
VDx reagents are currently implemented on Beckman Coulter, Olympus AU, Thermo Fisher Indiko Plus, Carolina Liquid Chemistries CLC1600, and Siemens Atellica analyzers. Do not see your analyzer listed? Talk with VDx. For qualified opportunities, we can evaluate additional chemistry analyzer implementations.
Explore the Full VDx Product Portfolio.
See the VDx reagent solutions, calibrators, controls, and analyzer compatibility designed to strengthen specimen-integrity testing.
View ProductsCommon Questions
Can your laboratory detect adulterants or substitution on drug tests? Here is what lab directors ask us most.
Contact UsWhat analyzers do VDx assays run on?
VDx reagents are currently implemented on Beckman Coulter, Olympus AU, Thermo Fisher Indiko Plus, Carolina Liquid Chemistries CLC1600, and Siemens Atellica analyzers. Do not see your analyzer listed? Talk with VDx. For qualified opportunities, we can evaluate additional chemistry analyzer implementations.
What is in the Essentials Panel?
The Essentials Panel brings together all six VDx tests: pH, urine creatinine, Specific Gravity Index, Oxidant History, and True Urine in Short Duration and Long Duration formats. It includes the calibrators and controls each test requires.
How is the Essentials Panel different from the SVT we run today?
Standard validity testing typically measures pH, creatinine, and specific gravity. The Essentials Panel keeps those foundation measures and adds VDx technology designed to identify specimen-integrity findings associated with synthetic urine, detox drinks, oxidants, and other forms of subversion.
How do I get pricing?
Talk with VDx at 855-826-5500 to discuss the opportunity and the right configuration for your laboratory or program.
Do I need an account to order?
VDx products are supplied through qualified laboratories, distributors, and program partners. Talk with VDx to discuss your needs; our team will guide you through qualification, account setup, and ordering.